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Hydromorphone may possibly increase the neuromuscular blocking action of skeletal muscle relaxants and create an elevated degree of respiratory despair.
Bodily dependence is a state that develops as a result of a physiological adaptation in reaction to recurring drug use, manifested by withdrawal signals and signs soon after abrupt discontinuation or a big dose reduction of the drug.
In these clients, mixed agonist/antagonist and partial agonist analgesics may possibly lessen the analgesic influence and/or precipitate withdrawal symptoms [see DRUG INTERACTIONS].
tell your physician and pharmacist if you are allergic to hydromorphone injection, another prescription drugs, sulfites, or any on the elements in hydromorphone injection solution. Talk to your pharmacist for a summary of the ingredients.
Androgen deficiency: Conditions of androgen deficiency have happened with use of opioids for an extended time period [see Medical PHARMACOLOGY].
To guard youthful little ones from poisoning, always lock security caps and here instantly place the medication in a secure spot – one which is up and away and out of their sight and get to.
Notify your healthcare supplier if you're taking any of the subsequent simply because these drugs connect with Viagra® and generic Viagra®:
DILAUDID INJECTION could impair the mental or Actual physical capabilities needed to carry out probably dangerous things to do for example driving a vehicle or working machinery.
Samples of other clinical circumstances you should focus on along with your healthcare supplier prior to getting hydromorphone or morphine contain:
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unexpected vision decline in one or both of those eyes. Sudden eyesight decline in one or both of those eyes generally is a sign of a serious eye issue referred to as non-arteritic anterior ischemic optic neuropathy (NAION).
To reduce the risk of respiratory despair, correct dosing and titration of DILAUDID INJECTION is essential [see DOSAGE AND ADMINISTRATION]. Overestimating the DILAUDID INJECTION dosage when changing individuals from One more opioid item can result in a lethal overdose with the very first dose.
The hydromorphone in DILAUDID INJECTION may possibly boost the frequency of seizures in people with seizure disorders and will boost the danger of seizures taking place in other medical settings connected to seizures.